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Basic Local Alignment Search Tool 2006-05-07
Basic Local Alignment Search Tool is a set of similarity search programs designed to explore all of the available databases. more>>
Basic Local Alignment Search Tool is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA.
It uses a heuristic algorithm which seeks local as opposed to global alignments, and is therefore able to detect relationships among sequences which share only isolated regions of similarity.
It can be run locally as a full executable, and can be used to run BLAST searches against private, local databases, or downloaded copies of the NCBI databases. It runs on Mac OS, Win32, LINUX, Solaris, IBM AIX, SGI, Compaq OSF, and HP- UX systems.
Main features:
Nucleotide
- Quickly search for highly similar sequences (megablast)
- Quickly search for divergent sequences (discontiguous megablast)
- Nucleotide-nucleotide BLAST (blastn)
- Search for short, nearly exact matches
- Search trace archives with megablast or discontiguous megablast
Protein
- Protein-protein BLAST (blastp)
- Position-specific iterated and pattern-hit initiated BLAST (PSI- and PHI-BLAST)
- Search for short, nearly exact matches
- Search the conserved domain database (rpsblast)
- Protein homology by domain architecture (cdart)
Translated
- Translated query vs. protein database (blastx)
- Protein query vs. translated database (tblastn)
- Translated query vs. translated database (tblastx)
Genomes
- Human, mouse, rat, chimp cow, pig, dog, sheep, cat
- Chicken, puffer fish, zebrafish
- Environmental samples
- Protozoa
- Insects, nematodes, plants, fungi, microbial genomes, other eukaryotic genomes
Special
- Search for gene expression data (GEO BLAST)
- Align two sequences (bl2seq)
- Screen for vector contamination (VecScreen)
- Immunoglobin BLAST (IgBlast)
- SNP BLAST
Meta
- Retrieve results
<<lessIt uses a heuristic algorithm which seeks local as opposed to global alignments, and is therefore able to detect relationships among sequences which share only isolated regions of similarity.
It can be run locally as a full executable, and can be used to run BLAST searches against private, local databases, or downloaded copies of the NCBI databases. It runs on Mac OS, Win32, LINUX, Solaris, IBM AIX, SGI, Compaq OSF, and HP- UX systems.
Main features:
Nucleotide
- Quickly search for highly similar sequences (megablast)
- Quickly search for divergent sequences (discontiguous megablast)
- Nucleotide-nucleotide BLAST (blastn)
- Search for short, nearly exact matches
- Search trace archives with megablast or discontiguous megablast
Protein
- Protein-protein BLAST (blastp)
- Position-specific iterated and pattern-hit initiated BLAST (PSI- and PHI-BLAST)
- Search for short, nearly exact matches
- Search the conserved domain database (rpsblast)
- Protein homology by domain architecture (cdart)
Translated
- Translated query vs. protein database (blastx)
- Protein query vs. translated database (tblastn)
- Translated query vs. translated database (tblastx)
Genomes
- Human, mouse, rat, chimp cow, pig, dog, sheep, cat
- Chicken, puffer fish, zebrafish
- Environmental samples
- Protozoa
- Insects, nematodes, plants, fungi, microbial genomes, other eukaryotic genomes
Special
- Search for gene expression data (GEO BLAST)
- Align two sequences (bl2seq)
- Screen for vector contamination (VecScreen)
- Immunoglobin BLAST (IgBlast)
- SNP BLAST
Meta
- Retrieve results
Download (14.6MB)
Added: 2006-06-14 License: Open Software License Price:
1228 downloads
Bio::Graphics::Glyph::alignment 1.4
Bio::Graphics::Glyph::alignment is the alignment glyph. more>>
Bio::Graphics::Glyph::alignment is the "alignment" glyph.
SYNOPSIS
See L< Bio::Graphics::Panel > and L< Bio::Graphics::Glyph >.
This is identical to the "graded_segments" glyph, and is used for drawing features that consist of discontinuous segments. The color intensity of each segment is proportionate to the score.
<<lessSYNOPSIS
See L< Bio::Graphics::Panel > and L< Bio::Graphics::Glyph >.
This is identical to the "graded_segments" glyph, and is used for drawing features that consist of discontinuous segments. The color intensity of each segment is proportionate to the score.
Download (4.7MB)
Added: 2006-10-21 License: Perl Artistic License Price:
1099 downloads
Local Area Security 0.5
L.A.S. is a research group focused on information security related subjects. more>>
Local Area Security is a research group focused on information security related subjects. We are most known for L.A.S. Linux. Our live-CD security toolkit.
Local Area Security is a project that was started in 2002 to research information security related topics. During that time there was no real live-CD toolkit focused on information security.
So Jascha, the project founder built one from a stripped down version of Knoppix called Model-K. Both of which were built from Debian Linux.
Up until version 0.4 L.A.S. Linux was command line only. Which made it limited to some of the tools it could contain since many require a GUI. Or at least for many it is preferable to have one. So FluxBox was added as the desktop since it is light weight and very feature filled.
It was during this time that Jascha came up with the idea of keeping the size of L.A.S. as small as possible, which lead to a target maximum size of 180MBs. The size of the original mini-CDs that were available at the time. This forced the selection of tools and features to be weighed heavily since unlike other live-CDs that throw in everything including the kitchen sink. L.A.S. was designed from the ground up to be a tool not a all-inclusive grab bag of applications.
As well as many advances for live-CDs came about, such as to-ram that allows booting a live-CD into the physical RAM of a computer. Which by chance L.A.S. was perfectly cut out for. With as little as 256MB of RAM people could boot L.A.S. and then free up their CD-ROMs for burring etc.
For forensics this was a big plus, along with many other uses. Plus L.A.S. ran very fast in RAM which helped with running Nessus, Nmap, or other tools. When compared to full size (700MB) CDs which would require 1GB of RAM to use the to-ram option, it was really no contest.
<<lessLocal Area Security is a project that was started in 2002 to research information security related topics. During that time there was no real live-CD toolkit focused on information security.
So Jascha, the project founder built one from a stripped down version of Knoppix called Model-K. Both of which were built from Debian Linux.
Up until version 0.4 L.A.S. Linux was command line only. Which made it limited to some of the tools it could contain since many require a GUI. Or at least for many it is preferable to have one. So FluxBox was added as the desktop since it is light weight and very feature filled.
It was during this time that Jascha came up with the idea of keeping the size of L.A.S. as small as possible, which lead to a target maximum size of 180MBs. The size of the original mini-CDs that were available at the time. This forced the selection of tools and features to be weighed heavily since unlike other live-CDs that throw in everything including the kitchen sink. L.A.S. was designed from the ground up to be a tool not a all-inclusive grab bag of applications.
As well as many advances for live-CDs came about, such as to-ram that allows booting a live-CD into the physical RAM of a computer. Which by chance L.A.S. was perfectly cut out for. With as little as 256MB of RAM people could boot L.A.S. and then free up their CD-ROMs for burring etc.
For forensics this was a big plus, along with many other uses. Plus L.A.S. ran very fast in RAM which helped with running Nessus, Nmap, or other tools. When compared to full size (700MB) CDs which would require 1GB of RAM to use the to-ram option, it was really no contest.
Download (210MB)
Added: 2005-11-09 License: GPL (GNU General Public License) Price:
840 downloads
Local Lyrics 1.0.2b
Local Lyrics is a python based amaroK-script requires amaroK 1.4! more>>
Local Lyrics is a python based amaroK-script requires amaroK 1.4!
I wrote simple wrappers for dcop-calls (using the shell-tool dcop), kdialog and amaroKs script system while writing this script. Use them if you want (its all LGPL) See the .tar.bz2s contense and: http://twoday.tuwien.ac.at/pub/stories/22759/
This lyrics-plugin simply scans a selected folder for textfiles with lyrics. This might be usefull when you have a lot of lyrics stored on your harddisc, but they are not available on lyrc.com.ar or a simmilar service.
Installation:
Open the lyrics-filesystem-x.x.amarokscript.tar.bz2 with amaroKs script managers script install option.
Usage:
Start the script with amaroKs script manager.
Select the directory in which the lyrics are stored.
The filenames of the lyrics have to be:
"artist - title.txt"
or
"title.txt"
Now amaroK will search this folder for lyrics, when there are none in its database for the current track.
<<lessI wrote simple wrappers for dcop-calls (using the shell-tool dcop), kdialog and amaroKs script system while writing this script. Use them if you want (its all LGPL) See the .tar.bz2s contense and: http://twoday.tuwien.ac.at/pub/stories/22759/
This lyrics-plugin simply scans a selected folder for textfiles with lyrics. This might be usefull when you have a lot of lyrics stored on your harddisc, but they are not available on lyrc.com.ar or a simmilar service.
Installation:
Open the lyrics-filesystem-x.x.amarokscript.tar.bz2 with amaroKs script managers script install option.
Usage:
Start the script with amaroKs script manager.
Select the directory in which the lyrics are stored.
The filenames of the lyrics have to be:
"artist - title.txt"
or
"title.txt"
Now amaroK will search this folder for lyrics, when there are none in its database for the current track.
Download (0.021MB)
Added: 2006-04-18 License: GPL (GNU General Public License) Price:
1286 downloads
Read Local Lyrics 1.1
Read Local Lyrics is a little Python script works as a lyrics plugin. more>>
Read Local Lyrics is a little Python script works as a lyrics plugin.
If to some audio file, a corresponding ".txt" file can be found in the same folder, this is taken as the lyrics of the song.
<<lessIf to some audio file, a corresponding ".txt" file can be found in the same folder, this is taken as the lyrics of the song.
Download (0.030MB)
Added: 2006-11-16 License: GPL (GNU General Public License) Price:
1072 downloads
Local IP Takeover 1.2
Local IP Takeover provides network link redundancy within a single server that has multiple network interface cards. more>>
Local IP Takeover provides network link redundancy within a single server that has multiple network interface cards (NICs) with each NIC connected to separate network switches.
If the primary NIC fails (i.e. it cannot ping its default gateway), the "service" IP (the IP that the outside world connects to) will automatically float to the secondary NIC and a specially crafted ARP (utilizing send_arp) will be broadcast on the local network, thereby instructing all other hosts to update their local ARP cache.
The result is minimal service downtime. Plus, no manual intervention is required in the event that a network card, cable, or switch breaks.
Enhancements:
- The initialization step is more robust and it doesnt allow lipt to abort its execution. Instead, lipt should recover to a sane state eventually (within less than half a minute under normal circumstances).
- Other minor fixes were made.
<<lessIf the primary NIC fails (i.e. it cannot ping its default gateway), the "service" IP (the IP that the outside world connects to) will automatically float to the secondary NIC and a specially crafted ARP (utilizing send_arp) will be broadcast on the local network, thereby instructing all other hosts to update their local ARP cache.
The result is minimal service downtime. Plus, no manual intervention is required in the event that a network card, cable, or switch breaks.
Enhancements:
- The initialization step is more robust and it doesnt allow lipt to abort its execution. Instead, lipt should recover to a sane state eventually (within less than half a minute under normal circumstances).
- Other minor fixes were made.
Download (0.011MB)
Added: 2007-05-16 License: GPL (GNU General Public License) Price:
892 downloads
Local Data Manager 6.6.5
Local Data Manager is a collection of cooperating programs that select, capture, manage, and distribute arbitrary data products. more>>
Local Data Manager (LDM) is a collection of cooperating programs that select, capture, manage, and distribute arbitrary data products.
The system is designed for event-driven data distribution, and is currently used in the Unidata Internet Data Distribution (IDD) project. The LDM system includes network client and server programs and their shared protocols.
An important characteristic of the LDM is its support for flexible, site-specific configuration.
Enhancements:
- Fixes for timestamp bugs.
<<lessThe system is designed for event-driven data distribution, and is currently used in the Unidata Internet Data Distribution (IDD) project. The LDM system includes network client and server programs and their shared protocols.
An important characteristic of the LDM is its support for flexible, site-specific configuration.
Enhancements:
- Fixes for timestamp bugs.
Download (0.61MB)
Added: 2007-08-09 License: BSD License Price:
809 downloads
System Local Audit Daemon 2.0
SLAD is a tool for performing local security checks against GNU/Linux systems. more>>
SLAD is a tool for performing local security checks against GNU/Linux systems.
SLAD has been primarily developed for the BOSS project to work together with Nessus to enhance its local scanning capabilities. For example, scanning for weak passwords with a tool like John-the-Ripper is something that simply cannot be achieved by a network scan.
Therefore, SLAD is required to be installed on every GNU/Linux system where local auditing needs to be done. SLAD can then be used as a stand-alone application or more conveniently through Nessus. For usage with Nessus two NASL plugins are provided for interfacing between Nessus and SLAD
The Version 2.0 provides a XML Interface for Parameters and easy integration of additional audit-parameters and tools. To help the administrator to integrate a new feature-set, a development-documentation is provided with the cvs.
SLAD has been tested and verified on the following platforms:
RedHat Fedora Core 3
SuSe 9.2
Debian 3.0 (woody)
Debian 3.1 (sarge)
ERPOSS3
Gentoo Linux 2004.3
SLAD is implemented in Perl and provides an extendable plugin architecture allowing to use various GPL-based security scanners and auditing tools under one common framework. Currently, SLAD comes packaged with
John-the-Ripper
Chkrootkit
LSOF
ClamAV
Tripwire
TIGER
As a result SLAD delivers reports of these locally installed auditing and analysis tools. When used with Nessus the individual reports are wrapped into a standard Nessus report.
SLAD as well as the SLAD NASL Plugins can be downloaded from this Website in their current stable release V2.0.
Installation:
You can use our "easy-to-use" GTK installer, this installer downloads the lastest SLAD Release Binary, and install it on the target system. You only need to provide the login for the traget system.
<<lessSLAD has been primarily developed for the BOSS project to work together with Nessus to enhance its local scanning capabilities. For example, scanning for weak passwords with a tool like John-the-Ripper is something that simply cannot be achieved by a network scan.
Therefore, SLAD is required to be installed on every GNU/Linux system where local auditing needs to be done. SLAD can then be used as a stand-alone application or more conveniently through Nessus. For usage with Nessus two NASL plugins are provided for interfacing between Nessus and SLAD
The Version 2.0 provides a XML Interface for Parameters and easy integration of additional audit-parameters and tools. To help the administrator to integrate a new feature-set, a development-documentation is provided with the cvs.
SLAD has been tested and verified on the following platforms:
RedHat Fedora Core 3
SuSe 9.2
Debian 3.0 (woody)
Debian 3.1 (sarge)
ERPOSS3
Gentoo Linux 2004.3
SLAD is implemented in Perl and provides an extendable plugin architecture allowing to use various GPL-based security scanners and auditing tools under one common framework. Currently, SLAD comes packaged with
John-the-Ripper
Chkrootkit
LSOF
ClamAV
Tripwire
TIGER
As a result SLAD delivers reports of these locally installed auditing and analysis tools. When used with Nessus the individual reports are wrapped into a standard Nessus report.
SLAD as well as the SLAD NASL Plugins can be downloaded from this Website in their current stable release V2.0.
Installation:
You can use our "easy-to-use" GTK installer, this installer downloads the lastest SLAD Release Binary, and install it on the target system. You only need to provide the login for the traget system.
Download (0.016MB)
Added: 2006-01-16 License: GPL (GNU General Public License) Price:
1380 downloads
Bio::AlignIO::msf 1.4
Bio::AlignIO::msf is a Perl module with msf sequence input/output stream. more>>
Bio::AlignIO::msf is a Perl module with msf sequence input/output stream.
SYNOPSIS
Do not use this module directly. Use it via the Bio::AlignIO class.
This object can transform Bio::Align::AlignI objects to and from msf flat file databases.
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _
next_aln
Title : next_aln
Usage : $aln = $stream->next_aln()
Function: returns the next alignment in the stream. Tries to read *all* MSF
It reads all non whitespace characters in the alignment
area. For MSFs with weird gaps (eg ~~~) map them by using
$al->map_chars(~,-)
Returns : L< Bio::Align::AlignI > object
Args : NONE
write_aln
Title : write_aln
Usage : $stream->write_aln(@aln)
Function: writes the $aln object into the stream in MSF format
Sequence type of the alignment is determined by the first sequence.
Returns : 1 for success and 0 for error
Args : L< Bio::Align::AlignI > object
<<lessSYNOPSIS
Do not use this module directly. Use it via the Bio::AlignIO class.
This object can transform Bio::Align::AlignI objects to and from msf flat file databases.
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _
next_aln
Title : next_aln
Usage : $aln = $stream->next_aln()
Function: returns the next alignment in the stream. Tries to read *all* MSF
It reads all non whitespace characters in the alignment
area. For MSFs with weird gaps (eg ~~~) map them by using
$al->map_chars(~,-)
Returns : L< Bio::Align::AlignI > object
Args : NONE
write_aln
Title : write_aln
Usage : $stream->write_aln(@aln)
Function: writes the $aln object into the stream in MSF format
Sequence type of the alignment is determined by the first sequence.
Returns : 1 for success and 0 for error
Args : L< Bio::Align::AlignI > object
Download (4.7MB)
Added: 2006-09-29 License: Perl Artistic License Price:
1121 downloads
nautilus-open-terminal 0.8 Alive
nautilus-open-terminal is a nautilus plugin for opening terminals in arbitrary local paths through nautilus. more>>
nautilus-open-terminal project is a nautilus plugin for opening terminals in arbitrary local paths through nautilus.
<<less Download (0.33MB)
Added: 2007-03-04 License: GPL (GNU General Public License) Price:
968 downloads
uplocalserver 0.1
uplocalserver is a service menu which you can copy a file on your local server. more>>
uplocalserver is a service menu which you can copy a file on your local server.
At the and youll have the file on the server and a direct link to it in the clipboard. If you want you can also change the name on the local server.
<<lessAt the and youll have the file on the server and a direct link to it in the clipboard. If you want you can also change the name on the local server.
Download (0.002MB)
Added: 2006-05-08 License: GPL (GNU General Public License) Price:
1266 downloads
Bio::Tools::AlignFactory 1.4
Bio::Tools::AlignFactory is a base object for alignment factories. more>>
Bio::Tools::AlignFactory is a base object for alignment factories.
SYNOPSIS
You wont be using this as an object, but using a dervied class like Bio::Tools::pSW
Holds common Alignment Factory attributes in place
<<lessSYNOPSIS
You wont be using this as an object, but using a dervied class like Bio::Tools::pSW
Holds common Alignment Factory attributes in place
Download (4.7MB)
Added: 2006-10-10 License: Perl Artistic License Price:
1111 downloads
Bio::AlignIO::bl2seq 1.4
Bio::AlignIO::bl2seq is a bl2seq sequence input/output stream. more>>
Bio::AlignIO::bl2seq is a bl2seq sequence input/output stream.
SYNOPSIS
Do not use this module directly. Use it via the Bio::AlignIO class, as in:
use Bio::AlignIO;
$in = Bio::AlignIO->new(-file => "inputfilename" , -format => bl2seq);
$aln = $in->next_aln();
This object can create Bio::SimpleAlign sequence alignment objects (of 2 sequences) from bl2seq BLAST reports.
A nice feature of this module is that- in combination with StandAloneBlast.pm or remote blasting - it can be used to align 2 sequences and make a SimpleAlign object from them which can then be manipulated using any SimpleAlign.pm methods, eg:
#Get 2 sequences
$str = Bio::SeqIO->new(-file=>t/amino.fa , -format => Fasta, );
my $seq3 = $str->next_seq();
my $seq4 = $str->next_seq();
# Run bl2seq on them
$factory = Bio::Tools::StandAloneBlast->new(program => blastp,
outfile => bl2seq.out);
my $bl2seq_report = $factory->bl2seq($seq3, $seq4);
# Use AlignIO.pm to create a SimpleAlign object from the bl2seq report
$str = Bio::AlignIO->new(-file=> bl2seq.out,-format => bl2seq);
$aln = $str->next_aln();
<<lessSYNOPSIS
Do not use this module directly. Use it via the Bio::AlignIO class, as in:
use Bio::AlignIO;
$in = Bio::AlignIO->new(-file => "inputfilename" , -format => bl2seq);
$aln = $in->next_aln();
This object can create Bio::SimpleAlign sequence alignment objects (of 2 sequences) from bl2seq BLAST reports.
A nice feature of this module is that- in combination with StandAloneBlast.pm or remote blasting - it can be used to align 2 sequences and make a SimpleAlign object from them which can then be manipulated using any SimpleAlign.pm methods, eg:
#Get 2 sequences
$str = Bio::SeqIO->new(-file=>t/amino.fa , -format => Fasta, );
my $seq3 = $str->next_seq();
my $seq4 = $str->next_seq();
# Run bl2seq on them
$factory = Bio::Tools::StandAloneBlast->new(program => blastp,
outfile => bl2seq.out);
my $bl2seq_report = $factory->bl2seq($seq3, $seq4);
# Use AlignIO.pm to create a SimpleAlign object from the bl2seq report
$str = Bio::AlignIO->new(-file=> bl2seq.out,-format => bl2seq);
$aln = $str->next_aln();
Download (4.7MB)
Added: 2007-08-10 License: Perl Artistic License Price:
812 downloads
AlignAid 0.0.2
AlignAid is a Perl module that easily run sequence alignments locally or on a cluster. more>>
AlignAid is a Perl module that easily run sequence alignments locally or on a cluster.
SYNOPSIS
use AlignAid;
# create an AlignAid object
# a single, locally run blast job is the default
my $job = AlignAid->new( db => my_blast_db, dir => $dir,
fasta => my_query.fa,
prog_args => V=20 -nonnegok );
# run the job on the current host
my $return_value = $job->submit(outfile => my_results.out);
# create an AlignAid cross_match object
# specify the alignment program and the queue to override the defaults
my $job2 = AlignAid->new( program => cross_match,
db => my_db.fa, dir => $dir,
fasta => my_query_seqs.fa, queue => LSF);
# submit the cross_match jobs to an LSF queue (of compute nodes)
my $return_value2 = $job2->submit(outfile => my_output);
# kill the queued jobs
my $return_value3 = $job2->kill_all;
AlignAid is designed to make it easy to run the sequence alignment programs Blast and cross_match. AlignAid can accept a large number of query sequences. If a compute cluster queue such as LSF or PBS is available, AlignAid can automatically split the queries into multiple queue jobs.
Likewise, if you want to run the alignments locally on a single host, a single change is all that is necessary -- AlignAid will take care of how to invoke the alignment programs and manage the output.
AlignAid also has rudimentary support for LSF queue job control; it is possible to kill jobs through AlignAids interface.
Enhancements:
- Perl
<<lessSYNOPSIS
use AlignAid;
# create an AlignAid object
# a single, locally run blast job is the default
my $job = AlignAid->new( db => my_blast_db, dir => $dir,
fasta => my_query.fa,
prog_args => V=20 -nonnegok );
# run the job on the current host
my $return_value = $job->submit(outfile => my_results.out);
# create an AlignAid cross_match object
# specify the alignment program and the queue to override the defaults
my $job2 = AlignAid->new( program => cross_match,
db => my_db.fa, dir => $dir,
fasta => my_query_seqs.fa, queue => LSF);
# submit the cross_match jobs to an LSF queue (of compute nodes)
my $return_value2 = $job2->submit(outfile => my_output);
# kill the queued jobs
my $return_value3 = $job2->kill_all;
AlignAid is designed to make it easy to run the sequence alignment programs Blast and cross_match. AlignAid can accept a large number of query sequences. If a compute cluster queue such as LSF or PBS is available, AlignAid can automatically split the queries into multiple queue jobs.
Likewise, if you want to run the alignments locally on a single host, a single change is all that is necessary -- AlignAid will take care of how to invoke the alignment programs and manage the output.
AlignAid also has rudimentary support for LSF queue job control; it is possible to kill jobs through AlignAids interface.
Enhancements:
- Perl
Download (0.34MB)
Added: 2007-01-22 License: Perl Artistic License Price:
1005 downloads
local-remote-controll-gui Beta 3
local-remote-controll-gui is a Lazarus/(freepascal) programmed software for running commands on remote server or machine. more>>
local-remote-controll-gui is a Lazarus/(freepascal) programmed software for running commands on remote "server" or machine, true a file shearing.(like sshfs..)... some customize options, GUI on the user/machine...linux ppc and linux x86, the source binary enabled.
<<less Download (4.4MB)
Added: 2007-05-01 License: GPL (GNU General Public License) Price:
906 downloads
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