SigInt 1.0
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SigInt 1.0 Ranking & Summary
File size:
0.34 MB
Platform:
Any Platform
License:
Freeware
Price:
Downloads:
981
Date added:
2007-02-15
Publisher:
Mount Sinai School of Medicine.
SigInt 1.0 description
SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.
The inputs to the program are: (a) a seed list of human Entrez Gene gene symbols, (b) a background networks in SIG format, and (c) a name for the output file (web-page file name with the htm extension). SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.
SigInt can be run on Linux, Mac and Windows operating systems and it requires a background network text file in SIG format.
Usage:
Extract the archive
chmod +x sigint_lnx.exe
./sigint_lnx.exe
The inputs to the program are: (a) a seed list of human Entrez Gene gene symbols, (b) a background networks in SIG format, and (c) a name for the output file (web-page file name with the htm extension). SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.
SigInt can be run on Linux, Mac and Windows operating systems and it requires a background network text file in SIG format.
Usage:
Extract the archive
chmod +x sigint_lnx.exe
./sigint_lnx.exe
SigInt 1.0 Screenshot
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