Mauve 2.0.0

Mauve project is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion.
Multiple genome alignment provides a basis for research into comparative genomics and the study of evolutionary dynamics on a new scale. Aligning whole genomes is a fundamentally different problem than aligning short sequences.
Mauve has been developed with the idea that a multiple genome aligner should require only modest computational resources. It employs algorithmic techniques that scale well in the amount of sequence being aligned.
For example, a pair of Y. pestis genomes can be aligned in under a minute, while a group of 9 divergent Enterobacterial genomes can be aligned in a few hours.
Enhancements:
- This release includes a new, accurate, and sensitive genome alignment algorithm called progressiveMauve.
- Hundreds of genomes can now be aligned, and rearranged segments conserved in subsets of the genomes can be identified.
- A new annotation search can find features by things like gene name and others.